We work at the interface of biology and engineering to develop new medical devices and human therapies. We create nanoparticles that can deliver genetic therapy inside of cells and even perform genome editing in vivo. We also develop living therapeutics, constructed from human cells and biomaterials, that can provide long-term therapy for chronic diseases like diabetes. Finally, we create smart biomaterials and responsive drug delivery systems that can integrate with the body and provide customized, on-demand treatment for patients.
Latest News
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Implantable islet cells could control diabetes without insulin injections
The cells can survive in the body for at least three months, producing enough insulin to control blood sugar levels.
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CSF1R inhibitor protects immunoisolated allo but not xeno transplants in primates
New results suggest that additional interventions may be needed to preserve xenogeneic grafts in higher-order species.
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Lipid Nanoparticle Database
Structure-function database and web tool to advance data-driven design for LNP engineering.